We just did this (though on another cruise line)! We landed Friday in Orlando and rented a car one way from MCO and return in Coco Beach. We had lunch and did some shopping in Disney Springs and then drove to Coco Beach. We stayed at the Four Points Sheraton literally on top of the Ron Jon surf shop. Excellent location! A block from the beach, near good food - I recommend Pancetta Pizza Bar - and a super short drive to the car rental. The next morning our rental company provides a shuttle to the cruise terminal for free (tip the driver a buck or two).

With the state of air travel the way it is right now, I can't advise ANYONE to fly in the day of their cruise or travel without trip insurance.

Have a fantastic trip!